POS88 SLOT FUNDAMENTALS EXPLAINED

to check the impression of many constraints on mutational tolerance throughout selection, we chose E. coli dihydrofolate reductase (DHFR) as a product system. DHFR is A vital enzyme in just folate metabolism that reduces dihydrofolate to tetrahydrofolate which is needed for thymidine creation. making use of this activity as The idea for an in vivo